My PC just did a check a few days ago and it came up clean, no virals or wares. I have McAfee on my laptop.
I just reinstalled the software and still gave me the same error, so I decied to reformat Zune, like stated on the sticky post. After reboot it still gave me the same error. This time I am going to reinstall the software again and not have the music files be linked in to it and do a complete from scratch setup, thinking maybe the proplem is with zune trying to incorrectly sync up with External HardDrive, even though it plays music just fine from the EHD.(Too much music not enough HD space).
I hope I can get it working, I will be super P.O.ed if I have to send it in, I have only had it for 6months.